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doi: 10.2471/BLT.10.076695 Wakefield M, Hayes L, Durkin S, et al

Details: Crafted for those who want the undiluted taste of American Spirit's premium, additive-free tobacco, this pack delivers an intense, full-flavored experience

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Reduced blood flow and exposure to tar and nicotine can also darken the melanin in the lips and gums, leading to uneven pigmentation

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